{"id":452,"date":"2019-03-12T14:59:47","date_gmt":"2019-03-12T14:59:47","guid":{"rendered":"http:\/\/clemson.world\/research\/?p=452"},"modified":"2019-03-12T20:28:45","modified_gmt":"2019-03-12T20:28:45","slug":"naren-vyavahare","status":"publish","type":"post","link":"https:\/\/clemson.world\/research\/naren-vyavahare\/","title":{"rendered":"Naren Vyavahare: Research with a Sense of Urgency"},"content":{"rendered":"<div id='fullscreen_slider_1'  class='avia-fullscreen-slider main_color   avia-builder-el-0  el_before_av_hr  avia-builder-el-first   container_wrap sidebar_right' style=' '  ><a href='#next-section' title='' class='scroll-down-link av-control-default' aria-hidden='true' data-av_icon='\ue877' data-av_iconfont='entypo-fontello'><\/a><div   data-size='no scaling'  data-lightbox_size='large'  data-animation='slide'  data-conditional_play=''  data-ids='520'  data-video_counter='0'  data-autoplay='false'  data-bg_slider='true'  data-slide_height='100'  data-handle='av_fullscreen'  data-interval='5'  data-class=' '  data-el_id=''  data-css_id='fullscreen_slider_1'  data-scroll_down='aviaTBscroll_down'  data-control_layout='av-control-default'  data-custom_markup=''  data-perma_caption=''  data-autoplay_stopper=''  data-image_attachment='scroll'  data-min_height='0px'  data-stretch=''  class='avia-slideshow avia-slideshow-1 av-slider-scroll-down-active av-control-default av-default-height-applied avia-slideshow-no scaling av_fullscreen   avia-slide-slider '  itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><ul class='avia-slideshow-inner ' style='padding-bottom: 66.6666666667%;' ><li style='background-position:top center;' data-img-url='https:\/\/clemson.world\/research\/wp-content\/uploads\/sites\/2\/2019\/03\/Naren-Vyavahare.jpg' class=' av-single-slide slide-1 ' ><div data-rel='slideshow-1' class='avia-slide-wrap '   ><\/div><\/li><\/ul><\/div><\/div><div id='after_full_slider_1'  class='main_color av_default_container_wrap container_wrap sidebar_right' style=' '  ><div class='container' ><div class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-452'><div class='entry-content-wrapper clearfix'>\n<div  style='height:50px' class='hr hr-invisible   avia-builder-el-1  el_after_av_fullscreen  el_before_av_one_full  avia-builder-el-first '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div>\n<div class=\"flex_column av_one_full  flex_column_div av-zero-column-padding first  avia-builder-el-2  el_after_av_hr  el_before_av_hr  \" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  av_inherit_color '  style='font-size:25px; color:#000000; '  itemprop=\"text\" ><p style=\"color: #f66733; font-size: 19px; font-weight: bolder; text-align: center; text-transform: uppercase; margin-bottom: -50px;\">Naren Vyavahare<\/p>\n<p style=\"font-size: 64px; font-weight: bolder; text-align: center; line-height: 1.1em;\">Research with a Sense of Urgency<\/p>\n<\/div><\/section><\/div>\n<div  style='height:1px; margin-top:-50px'  class='hr hr-invisible   avia-builder-el-4  el_after_av_one_full  el_before_av_one_full '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div>\n<div class=\"flex_column av_one_full  flex_column_div av-zero-column-padding first  avia-builder-el-5  el_after_av_hr  el_before_av_hr  \" style='border-radius:0px; '><div  style=' margin-top:30px; margin-bottom:30px;'  class='hr hr-custom hr-center hr-icon-no   avia-builder-el-6  avia-builder-el-no-sibling '><span class='hr-inner   inner-border-av-border-thin' style=' width:1100px;' ><span class='hr-inner-style'><\/span><\/span><\/div><\/div>\n<div  style='height:1px; margin-top:-50px'  class='hr hr-invisible   avia-builder-el-7  el_after_av_one_full  el_before_av_one_full '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div>\n<div class=\"flex_column av_one_full  flex_column_div av-zero-column-padding first  avia-builder-el-8  el_after_av_hr  el_before_av_hr  \" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  av_inherit_color '  style='font-size:25px; color:#000000; '  itemprop=\"text\" ><p style=\"font-weight: lighter; text-align: center;\">Vyavahare\u2019s career has been a response to his own experience with the world\u2019s suffering<\/p>\n<\/div><\/section><\/div><div  style='height:1px; margin-top:-50px'  class='hr hr-invisible   avia-builder-el-10  el_after_av_one_full  el_before_av_one_full '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div><\/p>\n<div class=\"flex_column av_one_full  flex_column_div av-zero-column-padding first  avia-builder-el-11  el_after_av_hr  el_before_av_three_fourth  \" style='border-radius:0px; '><div  style=' margin-top:30px; margin-bottom:30px;'  class='hr hr-custom hr-center hr-icon-no   avia-builder-el-12  avia-builder-el-no-sibling '><span class='hr-inner   inner-border-av-border-thin' style=' width:1100px;' ><span class='hr-inner-style'><\/span><\/span><\/div><\/div>\n<div class=\"flex_column av_three_fourth  flex_column_div av-zero-column-padding first  avia-builder-el-13  el_after_av_one_full  el_before_av_one_fourth  column-top-margin\" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  av_inherit_color '  style='font-size:19px; color:#000000; '  itemprop=\"text\" ><p class=\"p1\"><span class=\"s1\">Gr<\/span><span class=\"s2\">owing up in Pune, India,<\/span><span class=\"s1\"> Naren Vyavahare knew education was the key to his and his family\u2019s future. But his father drove a rented rickshaw, which generated enough income to cover day-to-day expenses but little else.<\/span><\/p>\n<p class=\"p3\"><span class=\"s1\">Vyavahare is now in the top echelons of bioengineers. As the Hunter Endowed Chair in Bioengineering, he oversees a grant currently worth more than $11 million. Since coming to Clemson, the bioengineer has attracted a total of more than $28 million in federal funding, including the largest single grant in Clemson\u2019s history, an NIH-funded Centers of Biomedical Research Excellence project that\u2019s attracted more than $20 million since 2009. That grant launched the S.C. Bioengineering Center for Regeneration and Formation of Tissues. SCBioCRAFT, a partnership with Prisma Health and the Medical University of South Carolina, has helped advance the field of cardiac and vascular tissue development through more than 300 peer-reviewed publications and papers. Vyavahare has launched three biotech companies based on the work.<\/span><\/p>\n<p class=\"p3\"><span class=\"s1\">In Pune, Vyavahare witnessed the healing work of hospitals and doctors. \u201cThese are people who are making differences,\u201d he recalls thinking. \u201cI need to work hard and go to that level somehow.\u201d<\/span><\/p>\n<p class=\"p3\"><span class=\"s1\">He earned a doctorate in chemistry and then, without the internet, without even a phone or a typewriter, \u201cwrote maybe 70, 80 letters to different professors\u201d in America, by hand.<\/span><\/p>\n<p class=\"p3\"><span class=\"s1\">One professor wrote him back: the most cited engineer in history, Robert Langer of Massachusetts Institute of Technology. Langer suggested Vyavahare contact Joachim Kohn, who was setting up his lab at Rutgers University. Vyavahare did, and Kohn faxed back an offer.<\/span><\/p>\n<p>In Kohn&#8217;s lab, Vyavahare learned about applying biomaterials to medical problems. He went to work with Robert Levy at the University of Michigan. When Levy accepted a position at Children&#8217;s Hospital of Philadelphia and the University of Pennsylvania, he brought Vyavahare along in a research faculty position.<\/p>\n<p>Vyavahare knew he had to leave Levy&#8217;s lab to reach his potential. &#8220;Small trees don&#8217;t grow in the shadows of big trees,&#8221; he says. &#8220;I talked with [Levy] about it, and he was OK.&#8221;<\/p>\n<p>Vyavahare had attended meetings of the Society of Biomaterials. He knew Clemson University had a hand in its formation; its first meeting was held in Clemson in 1975. So, he connected with then-chair Larry Dooley, who invited Vyavahare to give a lecture. He left with an offer to join the faculty. In 1999, his first year as a faculty member, he received his first $1 million grant from the NIH.<\/p>\n<p>Helping people continues to be the overriding theme in Vyavahare&#8217;s work: &#8220;There has to be some urgency for research. Don&#8217;t wait. People are suffering and dying every day. They are hoping the treatments will be developed for improving their lives. Urgency is needed in research and translating that research to effective treatments.&#8221;<\/p>\n<\/div><\/section><\/div>\n<div class=\"flex_column av_one_fourth  flex_column_div av-zero-column-padding   avia-builder-el-15  el_after_av_three_fourth  avia-builder-el-last  column-top-margin\" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  av_inherit_color '  style='font-size:16px; color:#000000; '  itemprop=\"text\" ><p><span style=\"color: #f66733; font-size: 19px; line-height: 1em;\"><strong>Excellence in Biomedical Research<\/strong><\/span><\/p>\n<p style=\"font-weight: lighter; line-height: 1.2em; margin: 10px 0px 10px 0px;\">Since 2009, Vyavahare\u2019s SCBioCRAFT tissue regeneration laboratory, initially funded by a grant from the NIH as a Center of Biomedical Research Excellence (COBRE), has led to the formation of four companies; 16 patents; $35 million in additional funding awarded to 23 faculty members; and numerous advancements in cardiac and vascular tissue development. That success laid the groundwork for NIH funding for two additional COBREs.<\/p>\n<p><strong>SC-TRIMH\u00a0<span style=\"color: #f66733;\">\u2192<\/span><\/strong><\/p>\n<p style=\"font-weight: lighter; line-height: 1.2em; margin: 5px 0px 0px 0px;\">In 2018, Clemson received an $11 million COBRE grant for the S.C. Center for Translational Research Improving Musculoskeletal Health, or SC-TRIMH, a project to change the way musculoskeletal disorders are diagnosed, treated and studied. SC-TRIMH combines orthopedics and other clinical expertise from Prisma Health and the Medical University of South Carolina with Clemson computer scientists, computational engineers and biophysicists. A major component of SC-TRIMH is the creation of \u201cvirtual clinical trials\u201d that will reduce time between concept and clinical practice.<\/p>\n<p><strong>EPIC\u00a0<span style=\"color: #f66733;\">\u2192<\/span><\/strong><\/p>\n<p style=\"font-weight: lighter; line-height: 1.2em; margin: 5px 0px 0px 0px;\">In 2016, a $10.5 million COBRE grant funded the Eukaryotic Pathogens Innovation Center&#8217;s study of the causative agents of some of the most devastating diseases, including malaria, amoebic dysentery, sleeping sickness, Chagas disease and fungal meningitis. EPIC investigators have generated more than $4.5 million in external funding and produced 35 publications. In addition, EPIC secured Clemson\u2019s first NIH training grant.<\/p>\n<\/div><\/section><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":13,"featured_media":520,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[4],"tags":[178,96,152,97,141,95,151],"coauthors":[11],"class_list":["post-452","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-faculty-profiles","tag-2019-faculty-profiles","tag-bioengineering","tag-epic","tag-india","tag-naren-vyavahare","tag-nih","tag-sc-trimh"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/clemson.world\/research\/wp-content\/uploads\/sites\/2\/2019\/03\/Naren-Vyavahare.jpg","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p9IEky-7i","_links":{"self":[{"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/posts\/452","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/comments?post=452"}],"version-history":[{"count":0,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/posts\/452\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/media\/520"}],"wp:attachment":[{"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/media?parent=452"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/categories?post=452"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/tags?post=452"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/clemson.world\/research\/wp-json\/wp\/v2\/coauthors?post=452"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}